PROTECTIVE MECHANISM OF GANDOU DECOCTION IN A COPPER-LADEN HEPATOLENTICULAR DEGENERATION MODEL: IN VITRO PHARMACOLOGY AND CELL METABOLOMICS

Protective Mechanism of Gandou Decoction in a Copper-Laden Hepatolenticular Degeneration Model: In Vitro Pharmacology and Cell Metabolomics

Gandou decoction (GDD) is a classic prescription for the treatment of hepatolenticular degeneration (HLD) in China; however, the liver-protecting mechanism of this Utensils prescription needs further evaluation.In the present study, we explored the protective mechanisms of GDD in a copper-laden HLD model using integrated pharmacology and cellular m

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A Mesoarchean Large Igneous Province on the Eastern Kaapvaal Craton (Southern Africa) Confirmed by Metavolcanic Rocks from Kubuta, Eswatini

AbstractMesoarchean magmatism is widespread on the eastern margin of the Kaapvaal Craton, but its origin is still poorly understood, mainly because geochemical data is rare.To shed some light on the source of this Mesoarchean magmatism and to relate different Mesoarchean volcanic sequences to each other, we provide major and trace element data as w

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